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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX16
All Species:
23.94
Human Site:
Y183
Identified Species:
40.51
UniProt:
O14662
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14662
NP_001001433.1
325
37031
Y183
F
R
H
A
Q
S
G
Y
L
K
R
M
K
N
R
Chimpanzee
Pan troglodytes
XP_514749
272
31071
S148
S
Q
H
F
F
D
T
S
V
P
L
M
D
D
G
Rhesus Macaque
Macaca mulatta
XP_001084615
321
36481
L180
R
H
A
Q
S
G
Y
L
K
R
M
K
N
R
E
Dog
Lupus familis
XP_853504
326
37253
Y184
F
R
R
A
Q
S
G
Y
L
K
R
M
K
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVI5
326
37034
Y184
F
R
H
A
Q
S
D
Y
L
K
R
M
K
N
R
Rat
Rattus norvegicus
O70257
261
29832
K138
G
F
P
E
D
S
S
K
E
K
N
F
V
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511120
304
34831
S180
S
Q
H
F
F
D
T
S
V
P
L
M
D
D
G
Chicken
Gallus gallus
NP_001006295
326
37263
Y184
F
R
H
A
Q
S
D
Y
L
K
R
M
K
S
R
Frog
Xenopus laevis
NP_001085029
304
35171
S180
S
K
H
F
F
D
T
S
V
P
L
I
D
D
G
Zebra Danio
Brachydanio rerio
XP_691316
324
37513
Y183
F
R
H
T
Q
S
G
Y
L
K
R
M
K
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
L168
R
P
T
N
D
D
E
L
E
K
M
L
E
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
E168
V
G
D
E
D
L
E
E
M
I
E
S
G
N
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SWH4
323
36414
R180
K
Q
S
T
Y
L
K
R
L
Q
Q
Q
K
E
G
Baker's Yeast
Sacchar. cerevisiae
Q08144
397
45857
Y183
F
R
V
L
Q
N
N
Y
L
K
F
L
N
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
97.2
95
N.A.
92.9
27.6
N.A.
82.4
88
78.1
78.7
N.A.
21.5
N.A.
21.5
N.A.
Protein Similarity:
100
83.6
98.1
96.9
N.A.
95.7
46.4
N.A.
88
95.4
88
90.4
N.A.
43
N.A.
41.8
N.A.
P-Site Identity:
100
13.3
0
93.3
N.A.
93.3
13.3
N.A.
13.3
86.6
6.6
93.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
33.3
6.6
93.3
N.A.
93.3
20
N.A.
33.3
93.3
33.3
93.3
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.6
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.9
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
29
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
22
29
15
0
0
0
0
0
22
22
8
% D
% Glu:
0
0
0
15
0
0
15
8
15
0
8
0
8
15
8
% E
% Phe:
43
8
0
22
22
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
8
8
0
0
0
8
22
0
0
0
0
0
8
0
36
% G
% His:
0
8
50
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% I
% Lys:
8
8
0
0
0
0
8
8
8
58
0
8
43
8
0
% K
% Leu:
0
0
0
8
0
15
0
15
50
0
22
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
15
50
0
0
0
% M
% Asn:
0
0
0
8
0
8
8
0
0
0
8
0
15
36
0
% N
% Pro:
0
8
8
0
0
0
0
0
0
22
0
0
0
0
8
% P
% Gln:
0
22
0
8
43
0
0
0
0
8
8
8
0
0
0
% Q
% Arg:
15
43
8
0
0
0
0
8
0
8
36
0
0
8
36
% R
% Ser:
22
0
8
0
8
43
8
22
0
0
0
8
0
15
0
% S
% Thr:
0
0
8
15
0
0
22
0
0
0
0
0
0
0
0
% T
% Val:
8
0
8
0
0
0
0
0
22
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
8
0
8
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _